Senna extract is an FDA-approved stimulant laxative effective for the short-term remedy of occasional constipation. Its primary benefit is promoting bowel movements by stimulating intestinal muscles.

Rheum palmatum (Rhubarb) extract effectively relieves constipation by stimulating bowel movements (peristalsis) and softening stool through its anthraquinone compounds, which increase water and electrolyte secretion in the colon and improve gut microbiota, making stools easier to pass. Traditional use and modern studies support it for short-term, occasional constipation relief, enhancing gut health and reducing straining.